Inefficient DNA Repair Is an Aging-Related Modifier of Parkinson’s Disease

The underlying relation between Parkinson’s disease (PD) etiopathology and its major risk factor, aging, is largely unknown. In light of the causative link between genome stability and aging, we investigate a possible nexus between DNA damage accumulation, aging, and PD by assessing aging-related DN...

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Vydáno v:Cell Rep
Hlavní autoři: Sepe, Sara, Milanese, Chiara, Gabriels, Sylvia, Derks, Kasper W.J., Payan-Gomez, Cesar, van IJcken, Wilfred F.J., Rijksen, Yvonne M.A., Nigg, Alex L., Moreno, Sandra, Cerri, Silvia, Blandini, Fabio, Hoeijmakers, Jan H.J., Mastroberardino, Pier G.
Médium: Artigo
Jazyk:Inglês
Vydáno: Cell Press 2016
Témata:
Report
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4893155/
https://ncbi.nlm.nih.gov/pubmed/27210754
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.04.071
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