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TLR-independent anti-inflammatory function of intestinal epithelial TRAF6 signalling prevents DSS-induced colitis in mice

OBJECTIVE: The gut microbiota modulates host susceptibility to intestinal inflammation, but the cell types and the signalling pathways orchestrating this bacterial regulation of intestinal homeostasis remain poorly understood. Here, we investigated the function of intestinal epithelial toll-like rec...

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Bibliografiske detaljer
Udgivet i:Gut
Main Authors: Vlantis, Katerina, Polykratis, Apostolos, Welz, Patrick-Simon, van Loo, Geert, Pasparakis, Manolis, Wullaert, Andy
Format: Artigo
Sprog:Inglês
Udgivet: BMJ Publishing Group 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4893119/
https://ncbi.nlm.nih.gov/pubmed/25761602
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/gutjnl-2014-308323
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