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NF-κB in the regulation of epithelial homeostasis and inflammation

The IκB kinase/NF-κB signaling pathway has been implicated in the pathogenesis of several inflammatory diseases. Increased activation of NF-κB is often detected in both immune and non-immune cells in tissues affected by chronic inflammation, where it is believed to exert detrimental functions by ind...

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Detalhes bibliográficos
Main Authors: Wullaert, Andy, Bonnet, Marion C, Pasparakis, Manolis
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3193399/
https://ncbi.nlm.nih.gov/pubmed/21151201
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/cr.2010.175
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