Crystal structure of Porphyromonas gingivalis peptidylarginine deiminase: implications for autoimmunity in rheumatoid arthritis

BACKGROUND: Periodontitis (PD) is a known risk factor for rheumatoid arthritis (RA) and there is increasing evidence that the link between the two diseases is due to citrullination by the unique bacterial peptidylarginine deiminase (PAD) enzyme expressed by periodontal pathogen Pophyromonas gingival...

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Bibliografske podrobnosti
izdano v:Ann Rheum Dis
Main Authors: Montgomery, Anna B, Kopec, Jolanta, Shrestha, Leela, Thezenas, Marie-Laetitia, Burgess-Brown, Nicola A, Fischer, Roman, Yue, Wyatt W, Venables, Patrick J
Format: Artigo
Jezik:Inglês
Izdano: BMJ Publishing Group 2016
Teme:
Basic and Translational Research
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4893104/
https://ncbi.nlm.nih.gov/pubmed/26209657
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2015-207656
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