Aberrant gene methylation in non-neoplastic mucosa as a predictive marker of ulcerative colitis-associated CRC

BACKGROUND PROMOTER: hypermethylation plays a major role in cancer through transcriptional silencing of critical genes. The aim of our study is to evaluate the methylation status of these genes in the colonic mucosa without dysplasia or adenocarcinoma at the different steps of sporadic and UC-relate...

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Detalhes bibliográficos
Publicado no:Oncotarget
Main Authors: Scarpa, Marco, Scarpa, Melania, Castagliuolo, Ignazio, Erroi, Francesca, Kotsafti, Andromachi, Basato, Silvia, Brun, Paola, D'Incà, Renata, Rugge, Massimo, Angriman, Imerio, Castoro, Carlo
Formato: Artigo
Idioma:Inglês
Publicado em: Impact Journals LLC 2016
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4891122/
https://ncbi.nlm.nih.gov/pubmed/26862732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7188
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