CD80-CD28 signaling controls the progression of inflammatory colorectal carcinogenesis

In patients with ulcerative colitis (UC) the cumulative risk of colon cancer is lower than the actual rate of dysplasia suggesting an efficient immune surveillance mechanism. Since the co-stimulatory molecule CD80 is overexpressed in dysplastic colonic mucosa of UC patients and T-cell activation ent...

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Veröffentlicht in:Oncotarget
Hauptverfasser: Scarpa, Marco, Brun, Paola, Scarpa, Melania, Morgan, Susan, Porzionato, Andrea, Kotsafti, Andromachi, Bortolami, Marina, Buda, Andrea, D'Incà, Renata, Macchi, Veronica, Sturniolo, Giacomo C., Rugge, Massimo, Bardini, Romeo, Castagliuolo, Ignazio, Angriman, Imerio, Castoro, Carlo
Format: Artigo
Sprache:Inglês
Veröffentlicht: Impact Journals LLC 2015
Schlagworte:
Research Paper
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4652987/
https://ncbi.nlm.nih.gov/pubmed/25595911
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