Weak Cytotoxic T Cells Activation Predicts Low-Grade Dysplasia Persistence in Ulcerative Colitis

In patients with ulcerative colitis (UC), dysplasia develops in 10%–20% of cases. The persistence of low-grade dysplasia (LGD) in UC in 2 consecutive observations is still an indication for restorative proctocolectomy. Our hypothesis is that in the case of weak cytotoxic activation, dysplasia persis...

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Pubblicato in:Clin Transl Gastroenterol
Autori principali: Kotsafti, Andromachi, D'Incà, Renata, Scarpa, Melania, Fassan, Matteo, Angriman, Imerio, Mescoli, Claudia, Bortoli, Nicolò, Brun, Paola, Bardini, Romeo, Rugge, Massimo, Savarino, Edoardo, Zingone, Fabiana, Castoro, Carlo, Castagliuolo, Ignazio, Scarpa, Marco
Natura: Artigo
Lingua:Inglês
Pubblicazione: Wolters Kluwer 2019
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6708661/
https://ncbi.nlm.nih.gov/pubmed/31343468
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.14309/ctg.0000000000000061
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