Aberrant gene methylation in non-neoplastic mucosa as a predictive marker of ulcerative colitis-associated CRC

BACKGROUND PROMOTER: hypermethylation plays a major role in cancer through transcriptional silencing of critical genes. The aim of our study is to evaluate the methylation status of these genes in the colonic mucosa without dysplasia or adenocarcinoma at the different steps of sporadic and UC-relate...

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Bibliografski detalji
Izdano u:Oncotarget
Glavni autori: Scarpa, Marco, Scarpa, Melania, Castagliuolo, Ignazio, Erroi, Francesca, Kotsafti, Andromachi, Basato, Silvia, Brun, Paola, D'Incà, Renata, Rugge, Massimo, Angriman, Imerio, Castoro, Carlo
Format: Artigo
Jezik:Inglês
Izdano: Impact Journals LLC 2016
Teme:
Research Paper
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4891122/
https://ncbi.nlm.nih.gov/pubmed/26862732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7188
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