Aberrant gene methylation in non-neoplastic mucosa as a predictive marker of ulcerative colitis-associated CRC

BACKGROUND PROMOTER: hypermethylation plays a major role in cancer through transcriptional silencing of critical genes. The aim of our study is to evaluate the methylation status of these genes in the colonic mucosa without dysplasia or adenocarcinoma at the different steps of sporadic and UC-relate...

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Bibliografische gegevens
Gepubliceerd in:Oncotarget
Hoofdauteurs: Scarpa, Marco, Scarpa, Melania, Castagliuolo, Ignazio, Erroi, Francesca, Kotsafti, Andromachi, Basato, Silvia, Brun, Paola, D'Incà, Renata, Rugge, Massimo, Angriman, Imerio, Castoro, Carlo
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: Impact Journals LLC 2016
Onderwerpen:
Research Paper
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4891122/
https://ncbi.nlm.nih.gov/pubmed/26862732
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7188
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