Splicing factor mutations predict poor prognosis in patients with de novo acute myeloid leukemia

Mutations in splicing factor (SF) genes are frequently detected in myelodysplastic syndrome, but the prognostic relevance of these genes mutations in acute myeloid leukemia (AML) remains unclear. In this study, we investigated mutations of three SF genes, SF3B1, U2AF1 and SRSF2, by Sanger sequencing...

Descripción completa

Guardado en:
Detalles Bibliográficos
Publicado en:Oncotarget
Autores principales: Hou, Hsin-An, Liu, Chieh-Yu, Kuo, Yuan-Yeh, Chou, Wen-Chien, Tsai, Cheng-Hong, Lin, Chien-Chin, Lin, Liang-In, Tseng, Mei-Hsuan, Chiang, Ying-Chieh, Liu, Ming-Chih, Liu, Chia-Wen, Tang, Jih-Luh, Yao, Ming, Li, Chi-Cheng, Huang, Shang-Yi, Ko, Bor-Sheng, Hsu, Szu-Chun, Chen, Chien-Yuan, Lin, Chien-Ting, Wu, Shang-Ju, Tsay, Woei, Tien, Hwei-Fang
Formato: Artigo
Lenguaje:Inglês
Publicado: Impact Journals LLC 2016
Materias:
Research Paper
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4891028/
https://ncbi.nlm.nih.gov/pubmed/26812887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7000
Etiquetas: Agregar Etiqueta
Sin Etiquetas, Sea el primero en etiquetar este registro!

Ejemplares similares