Higher Decorin Levels in Bone Marrow Plasma Are Associated with Superior Treatment Response to Novel Agent-Based Induction in Patients with Newly Diagnosed Myeloma - A Retrospective Study

The growth of myeloma cells depends on bone marrow (BM) stroma consisting of stromal cells, secreted cytokines and the extracellular matrix (ECM). Decorin, a small leucine-rich proteoglycan in the ECM, is a signaling ligand and native anti-tumor agent. However, the role of decorin in patients with m...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Huang, Shang-Yi, Lin, Hsiu-Hsia, Yao, Ming, Tang, Jih-Luh, Wu, Shang-Ju, Hou, Hsin-An, Chou, Wen-Chien, Chou, Sheng-Chieh, Hsu, Szu-Chun, Ko, Bor-Sheng, Lu, Hsiao-Yun, Tsay, Woei, Tien, Hwei-Fang
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4574783/
https://ncbi.nlm.nih.gov/pubmed/26379028
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0137552
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