Splicing factor mutations predict poor prognosis in patients with de novo acute myeloid leukemia

Mutations in splicing factor (SF) genes are frequently detected in myelodysplastic syndrome, but the prognostic relevance of these genes mutations in acute myeloid leukemia (AML) remains unclear. In this study, we investigated mutations of three SF genes, SF3B1, U2AF1 and SRSF2, by Sanger sequencing...

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Publicado en:Oncotarget
Main Authors: Hou, Hsin-An, Liu, Chieh-Yu, Kuo, Yuan-Yeh, Chou, Wen-Chien, Tsai, Cheng-Hong, Lin, Chien-Chin, Lin, Liang-In, Tseng, Mei-Hsuan, Chiang, Ying-Chieh, Liu, Ming-Chih, Liu, Chia-Wen, Tang, Jih-Luh, Yao, Ming, Li, Chi-Cheng, Huang, Shang-Yi, Ko, Bor-Sheng, Hsu, Szu-Chun, Chen, Chien-Yuan, Lin, Chien-Ting, Wu, Shang-Ju, Tsay, Woei, Tien, Hwei-Fang
Formato: Artigo
Idioma:Inglês
Publicado: Impact Journals LLC 2016
Assuntos:
Research Paper
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4891028/
https://ncbi.nlm.nih.gov/pubmed/26812887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7000
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