Splicing factor mutations predict poor prognosis in patients with de novo acute myeloid leukemia

Mutations in splicing factor (SF) genes are frequently detected in myelodysplastic syndrome, but the prognostic relevance of these genes mutations in acute myeloid leukemia (AML) remains unclear. In this study, we investigated mutations of three SF genes, SF3B1, U2AF1 and SRSF2, by Sanger sequencing...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Oncotarget
Päätekijät: Hou, Hsin-An, Liu, Chieh-Yu, Kuo, Yuan-Yeh, Chou, Wen-Chien, Tsai, Cheng-Hong, Lin, Chien-Chin, Lin, Liang-In, Tseng, Mei-Hsuan, Chiang, Ying-Chieh, Liu, Ming-Chih, Liu, Chia-Wen, Tang, Jih-Luh, Yao, Ming, Li, Chi-Cheng, Huang, Shang-Yi, Ko, Bor-Sheng, Hsu, Szu-Chun, Chen, Chien-Yuan, Lin, Chien-Ting, Wu, Shang-Ju, Tsay, Woei, Tien, Hwei-Fang
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Impact Journals LLC 2016
Aiheet:
Research Paper
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4891028/
https://ncbi.nlm.nih.gov/pubmed/26812887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7000
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