Splicing factor mutations predict poor prognosis in patients with de novo acute myeloid leukemia

Mutations in splicing factor (SF) genes are frequently detected in myelodysplastic syndrome, but the prognostic relevance of these genes mutations in acute myeloid leukemia (AML) remains unclear. In this study, we investigated mutations of three SF genes, SF3B1, U2AF1 and SRSF2, by Sanger sequencing...

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Detaylı Bibliyografya
Yayımlandı:Oncotarget
Asıl Yazarlar: Hou, Hsin-An, Liu, Chieh-Yu, Kuo, Yuan-Yeh, Chou, Wen-Chien, Tsai, Cheng-Hong, Lin, Chien-Chin, Lin, Liang-In, Tseng, Mei-Hsuan, Chiang, Ying-Chieh, Liu, Ming-Chih, Liu, Chia-Wen, Tang, Jih-Luh, Yao, Ming, Li, Chi-Cheng, Huang, Shang-Yi, Ko, Bor-Sheng, Hsu, Szu-Chun, Chen, Chien-Yuan, Lin, Chien-Ting, Wu, Shang-Ju, Tsay, Woei, Tien, Hwei-Fang
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Impact Journals LLC 2016
Konular:
Research Paper
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4891028/
https://ncbi.nlm.nih.gov/pubmed/26812887
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.7000
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