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Long non-coding RNA HOXB-AS3 promotes myeloid cell proliferation and its higher expression is an adverse prognostic marker in patients with acute myeloid leukemia and myelodysplastic syndrome

BACKGROUND: Long non-coding RNAs (lncRNAs) represent the majority of cellular transcripts and play pivotal roles in hematopoiesis. However, their clinical relevance in acute myeloid leukemia (AML) and myelodysplastic syndrome (MDS) remains largely unknown. Here, we investigated the functions of HOXB...

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Détails bibliographiques
Publié dans:BMC Cancer
Auteurs principaux: Huang, Huai-Hsuan, Chen, Fei-Yun, Chou, Wen-Chien, Hou, Hsin-An, Ko, Bor-Sheng, Lin, Chien-Ting, Tang, Jih-Luh, Li, Chi-Cheng, Yao, Ming, Tsay, Woei, Hsu, Szu-Chun, Wu, Shang-Ju, Chen, Chien-Yuan, Huang, Shang-Yi, Tseng, Mei-Hsuan, Tien, Hwei-Fang, Chen, Ruey-Hwa
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2019
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6591843/
https://ncbi.nlm.nih.gov/pubmed/31234830
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-019-5822-y
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