Adenovirus-mediated downregulation of the ubiquitin ligase RNF8 sensitizes bladder cancer to radiotherapy

The ubiquitin ligase RNF8 promotes the DNA damage response (DDR). We observed that the expression of RNF8 was increased in bladder cancer cells and that this change in RNF8 expression could be reversed by adenovirus-mediated shRNA treatment. Moreover, we found that RNF8 knockdown sensitized bladder...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:Oncotarget
Päätekijät: Zhao, Mei-Jun, Song, Yan-Feng, Niu, Hai-Tao, Tian, Ying-Xia, Yang, Xu-Guang, Xie, Kun, Jing, Yu-Hong, Wang, De-Gui
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: Impact Journals LLC 2016
Aiheet:
Research Paper
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC4891017/
https://ncbi.nlm.nih.gov/pubmed/26788910
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.6909
Tagit: Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!

Samankaltaisia teoksia