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Saccharomyces cerevisiae Tti2 Regulates PIKK Proteins and Stress Response

The TTT complex is composed of the three essential proteins Tel2, Tti1, and Tti2. The complex is required to maintain steady state levels of phosphatidylinositol 3-kinase-related kinase (PIKK) proteins, including mTOR, ATM/Tel1, ATR/Mec1, and TRRAP/Tra1, all of which serve as regulators of critical...

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Detalles Bibliográficos
Publicado en:G3 (Bethesda)
Main Authors: Hoffman, Kyle S., Duennwald, Martin L., Karagiannis, Jim, Genereaux, Julie, McCarton, Alexander S., Brandl, Christopher J.
Formato: Artigo
Idioma:Inglês
Publicado: Genetics Society of America 2016
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889661/
https://ncbi.nlm.nih.gov/pubmed/27172216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.116.029520
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