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Saccharomyces cerevisiae Tti2 Regulates PIKK Proteins and Stress Response

The TTT complex is composed of the three essential proteins Tel2, Tti1, and Tti2. The complex is required to maintain steady state levels of phosphatidylinositol 3-kinase-related kinase (PIKK) proteins, including mTOR, ATM/Tel1, ATR/Mec1, and TRRAP/Tra1, all of which serve as regulators of critical...

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Foilsithe in:G3 (Bethesda)
Main Authors: Hoffman, Kyle S., Duennwald, Martin L., Karagiannis, Jim, Genereaux, Julie, McCarton, Alexander S., Brandl, Christopher J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: Genetics Society of America 2016
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Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889661/
https://ncbi.nlm.nih.gov/pubmed/27172216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.116.029520
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