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Saccharomyces cerevisiae Tti2 Regulates PIKK Proteins and Stress Response

The TTT complex is composed of the three essential proteins Tel2, Tti1, and Tti2. The complex is required to maintain steady state levels of phosphatidylinositol 3-kinase-related kinase (PIKK) proteins, including mTOR, ATM/Tel1, ATR/Mec1, and TRRAP/Tra1, all of which serve as regulators of critical...

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Bibliografiske detaljer
Udgivet i:G3 (Bethesda)
Main Authors: Hoffman, Kyle S., Duennwald, Martin L., Karagiannis, Jim, Genereaux, Julie, McCarton, Alexander S., Brandl, Christopher J.
Format: Artigo
Sprog:Inglês
Udgivet: Genetics Society of America 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889661/
https://ncbi.nlm.nih.gov/pubmed/27172216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.116.029520
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