Evolving Mistranslating tRNAs Through a Phenotypically Ambivalent Intermediate in Saccharomyces cerevisiae

The genetic code converts information from nucleic acid into protein. The genetic code was thought to be immutable, yet many examples in nature indicate that variations to the code provide a selective advantage. We used a sensitive selection system involving suppression of a deleterious allele (tti2...

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Bibliografski detalji
Izdano u:Genetics
Glavni autori: Berg, Matthew D., Hoffman, Kyle S., Genereaux, Julie, Mian, Safee, Trussler, Ryan S., Haniford, David B., O’Donoghue, Patrick, Brandl, Christopher J.
Format: Artigo
Jezik:Inglês
Izdano: Genetics Society of America 2017
Teme:
Investigations
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC5560794/
https://ncbi.nlm.nih.gov/pubmed/28576863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/genetics.117.203232
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