Genetic selection for mistranslation rescues a defective co-chaperone in yeast

Despite the general requirement for translation fidelity, mistranslation can be an adaptive response. We selected spontaneous second site mutations that suppress the stress sensitivity caused by a Saccharomyces cerevisiae tti2 allele with a Leu to Pro mutation at residue 187, identifying a single nu...

Fuld beskrivelse

Na minha lista:
Bibliografiske detaljer
Udgivet i:Nucleic Acids Res
Main Authors: Hoffman, Kyle S., Berg, Matthew D., Shilton, Brian H., Brandl, Christopher J., O'Donoghue, Patrick
Format: Artigo
Sprog:Inglês
Udgivet: Oxford University Press 2017
Fag:
RNA
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5389508/
https://ncbi.nlm.nih.gov/pubmed/27899648
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkw1021
Tags: Tilføj Tag
Ingen Tags, Vær først til at tagge denne postø!

Lignende værker