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The Pseudokinase Domain of Saccharomyces cerevisiae Tra1 Is Required for Nuclear Localization and Incorporation into the SAGA and NuA4 Complexes

Tra1 is an essential component of the SAGA/SLIK and NuA4 complexes in S. cerevisiae, recruiting these co-activator complexes to specific promoters. As a PIKK family member, Tra1 is characterized by a C-terminal phosphoinositide 3-kinase (PI3K) domain. Unlike other PIKK family members (e.g., Tor1, To...

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Detalhes bibliográficos
Publicado no:G3 (Bethesda)
Main Authors: Berg, Matthew D., Genereaux, Julie, Karagiannis, Jim, Brandl, Christopher J.
Formato: Artigo
Idioma:Inglês
Publicado em: Genetics Society of America 2018
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5982823/
https://ncbi.nlm.nih.gov/pubmed/29626083
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.118.200288
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