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Architecture of the Saccharomyces cerevisiae NuA4/TIP60 complex

The NuA4/TIP60 acetyltransferase complex is required for gene regulation, DNA repair and cell cycle progression. The limited structural information impeded understanding of NuA4/TIP60 assembly and regulatory mechanism. Here, we report the 4.7 Å cryo-electron microscopy (cryo-EM) structure of a NuA4/...

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Bibliografiske detaljer
Udgivet i:Nat Commun
Main Authors: Wang, Xuejuan, Ahmad, Salar, Zhang, Zhihui, Côté, Jacques, Cai, Gang
Format: Artigo
Sprog:Inglês
Udgivet: Nature Publishing Group UK 2018
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5861120/
https://ncbi.nlm.nih.gov/pubmed/29559617
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41467-018-03504-5
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