The C-terminal Residues of Saccharomyces cerevisiae Mec1 Are Required for Its Localization, Stability, and Function

Mec1, a member of the phosphoinositide three-kinase-related kinase (PIKK) family of proteins, is involved in the response to replicative stress and DNA damage and in telomere maintenance. An essential 30 to 35 residue, the FATC domain is found at the C-terminus of all PIKK family members. To investi...

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Detaylı Bibliyografya
Asıl Yazarlar: DaSilva, Lance F., Pillon, Samantha, Genereaux, Julie, Davey, Megan J., Gloor, Gregory B., Karagiannis, Jim, Brandl, Christopher J.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Genetics Society of America 2013
Konular:
Investigations
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3789791/
https://ncbi.nlm.nih.gov/pubmed/23934994
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1534/g3.113.006841
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