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Formation of Chromosomal Domains by Loop Extrusion
Topologically Associating Domains (TADs) are fundamental structural and functional building blocks of human interphase chromosomes, yet mechanisms of TAD formation remain unclear. Here we propose that loop extrusion underlies TAD formation. In this process, cis-acting loop-extruding factors, likely...
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| Publicado no: | Cell Rep |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4889513/ https://ncbi.nlm.nih.gov/pubmed/27210764 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.celrep.2016.04.085 |
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