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GSH-dependent antioxidant defense contributes to the acclimation of colon cancer cells to acidic microenvironment
Due to increased glycolysis and poor local perfusion, solid tumors are usually immersed in an acidic microenvironment. While extracellular acidosis is cytotoxic, cancer cells eventually become acclimated to it. While previous studies have addressed the acute effect of acidosis on cancer cells, littl...
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| Pubblicato in: | Cell Cycle |
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| Autori principali: | , , , , , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Taylor & Francis
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4889284/ https://ncbi.nlm.nih.gov/pubmed/26950675 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2016.1158374 |
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