GSH-dependent antioxidant defense contributes to the acclimation of colon cancer cells to acidic microenvironment

Due to increased glycolysis and poor local perfusion, solid tumors are usually immersed in an acidic microenvironment. While extracellular acidosis is cytotoxic, cancer cells eventually become acclimated to it. While previous studies have addressed the acute effect of acidosis on cancer cells, littl...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Cell Cycle
Prif Awduron: Zhao, Minnan, Liu, Qiao, Gong, Yanchao, Xu, Xiuhua, Zhang, Chen, Liu, Xiaojie, Zhang, Caibo, Guo, Haiyang, Zhang, Xiyu, Gong, Yaoqin, Shao, Changshun
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Taylor & Francis 2016
Pynciau:
Report
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889284/
https://ncbi.nlm.nih.gov/pubmed/26950675
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2016.1158374
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