Lack of interferon-γ receptor results in a microenvironment favorable for intestinal tumorigenesis

IFN-γ plays an important role in innate and adaptive immunity. IFN-γ signaling is also involved in tumorigenesis, with both pro- and antitumor activities documented. We here report the characterization of intestinal tumorigenesis in Apc(Min/+) mice that lack IFN-γ receptor. We observed that Ifngr1(−...

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發表在:Oncotarget
Main Authors: Zhang, Caibo, Hou, Dong, Wei, Haifeng, Zhao, Minnan, Yang, Lin, Liu, Qiao, Zhang, Xiyu, Gong, Yaoqin, Shao, Changshun
格式: Artigo
語言:Inglês
出版: Impact Journals LLC 2016
主題:
Research Paper
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC5173119/
https://ncbi.nlm.nih.gov/pubmed/27286456
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.18632/oncotarget.9867
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