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Impaired rejection and mucosal injury of small intestinal allografts lacking the interferon-γ receptor
Small intestinal mucosal T cell activation results in villous atrophy and crypt hyperplasia. There is conflicting evidence as to whether a Th1 IFN-γ response may be involved. Using a murine intestinal transplant model of T cell-mediated enteropathy we aimed to study the role of IFN-γ on the developm...
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| Auteurs principaux: | , , , , |
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| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
Blackwell Science Inc
2003
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2517553/ https://ncbi.nlm.nih.gov/pubmed/12974940 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1046/j.1365-2613.2003.00342.x |
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