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APOBEC3A damages the cellular genome during DNA replication

The human APOBEC3 family of DNA-cytosine deaminases comprises 7 members (A3A-A3H) that act on single-stranded DNA (ssDNA). The APOBEC3 proteins function within the innate immune system by mutating DNA of viral genomes and retroelements to restrict infection and retrotransposition. Recent evidence su...

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Publicat a:Cell Cycle
Autors principals: Green, Abby M., Landry, Sébastien, Budagyan, Konstantin, Avgousti, Daphne C., Shalhout, Sophia, Bhagwat, Ashok S., Weitzman, Matthew D.
Format: Artigo
Idioma:Inglês
Publicat: Taylor & Francis 2016
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4889253/
https://ncbi.nlm.nih.gov/pubmed/26918916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/15384101.2016.1152426
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