Adenovirus Core Protein VII Downregulates the DNA Damage Response on the Host Genome

Viral manipulation of cellular proteins allows viruses to suppress host defenses and generate infectious progeny. Due to the linear double-stranded DNA nature of the adenovirus genome, the cellular DNA damage response (DDR) is considered a barrier to successful infection. The adenovirus genome is pa...

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Bibliographische Detailangaben
Veröffentlicht in:J Virol
Hauptverfasser: Avgousti, Daphne C., Della Fera, Ashley N., Otter, Clayton J., Herrmann, Christin, Pancholi, Neha J., Weitzman, Matthew D.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Microbiology 2017
Schlagworte:
Virus-Cell Interactions
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5625504/
https://ncbi.nlm.nih.gov/pubmed/28794020
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01089-17
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