A core viral protein binds host nucleosomes to sequester immune danger signals

Viral proteins mimic host protein structure and function to redirect cellular processes and subvert innate defenses(1). Small basic proteins compact and regulate both viral and cellular DNA genomes. Nucleosomes are the repeating units of cellular chromatin and play an important role in innate immune...

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Publicado no:Nature
Main Authors: Avgousti, Daphne C., Herrmann, Christin, Kulej, Katarzyna, Pancholi, Neha J., Sekulic, Nikolina, Petrescu, Joana, Molden, Rosalynn C., Blumenthal, Daniel, Paris, Andrew J., Reyes, Emigdio D., Ostapchuk, Philomena, Hearing, Patrick, Seeholzer, Steven H., Worthen, G. Scott, Black, Ben E., Garcia, Benjamin A., Weitzman, Matthew D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4950998/
https://ncbi.nlm.nih.gov/pubmed/27362237
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature18317
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