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APOBEC3 proteins and genomic stability: The high cost of a good defense

The human APOBEC3 family of cytidine deaminases constitutes a cellular intrinsic defense mechanism that is effective against a range of viruses and retro-elements. While it is well-established that these enzymes are powerful mutators of viral DNA, the possibility that their activity could threaten t...

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Detalhes bibliográficos
Main Authors: Narvaiza, Iñigo, Landry, Sébastien, Weitzman, Matthew D
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3272230/
https://ncbi.nlm.nih.gov/pubmed/22157092
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/cc.11.1.18706
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