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Nurturing the genome: A-type lamins preserve genomic stability

A-type lamins provide a scaffold for tethering chromatin and protein complexes regulating nuclear structure and function. Interest in lamins increased after mutations in the LMNA gene were found to be associated with a variety of human disorders termed laminopathies. These include muscular dystrophy...

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Autori principali: Gonzalez-Suarez, Ignacio, Gonzalo, Susana
Natura: Artigo
Lingua:Inglês
Pubblicazione: Landes Bioscience 2010
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3030686/
https://ncbi.nlm.nih.gov/pubmed/21326943
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/nucl.1.2.10797
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