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Molecular and cellular insights into T cell exhaustion
In chronic infections and cancer, T cells are exposed to persistent antigen and/or inflammatory signals. This scenario is often associated with the deterioration of T cell function: a state called ‘exhaustion’. Exhausted T cells lose robust effector functions, express multiple inhibitory receptors a...
Shranjeno v:
| izdano v: | Nat Rev Immunol |
|---|---|
| Main Authors: | , |
| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2015
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4889009/ https://ncbi.nlm.nih.gov/pubmed/26205583 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nri3862 |
| Oznake: |
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