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Tumor-infiltrating CD8(+) T cell antitumor efficacy and exhaustion: molecular insights

Host immunity has an essential role in the clinical management of cancers. Therefore, it is advantageous to choose therapies that can promote tumor cell death and concurrently boost host immunity. The dynamic tumor microenvironment (TME) determines whether an antineoplastic drug will elicit favorabl...

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Détails bibliographiques
Publié dans:Drug Discov Today
Auteurs principaux: Kumar, Sandeep, Singh, Sunil Kumar, Rana, Basabi, Rana, Ajay
Format: Artigo
Langue:Inglês
Publié: 2021
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC8131230/
https://ncbi.nlm.nih.gov/pubmed/33450394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2021.01.002
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