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Tumor-infiltrating CD8(+) T cell antitumor efficacy and exhaustion: molecular insights

Host immunity has an essential role in the clinical management of cancers. Therefore, it is advantageous to choose therapies that can promote tumor cell death and concurrently boost host immunity. The dynamic tumor microenvironment (TME) determines whether an antineoplastic drug will elicit favorabl...

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Dades bibliogràfiques
Publicat a:Drug Discov Today
Autors principals: Kumar, Sandeep, Singh, Sunil Kumar, Rana, Basabi, Rana, Ajay
Format: Artigo
Idioma:Inglês
Publicat: 2021
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC8131230/
https://ncbi.nlm.nih.gov/pubmed/33450394
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.drudis.2021.01.002
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