Lataa...
The use of isomeric testosterone dimers to explore allosteric effects in substrate binding to cytochrome P450 CYP3A4
Cytochrome P450 CYP3A4 is the main drug-metabolizing enzyme in the human liver, being responsible for oxidation of ~ 50% of all pharmaceuticals metabolized by human P450 enzymes. Possessing a relatively large substrate-binding pocket, it can simultaneously bind several substrate molecules and thus o...
Tallennettuna:
| Julkaisussa: | J Inorg Biochem |
|---|---|
| Päätekijät: | , , , , , , |
| Aineistotyyppi: | Artigo |
| Kieli: | Inglês |
| Julkaistu: |
2015
|
| Aiheet: | |
| Linkit: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4887402/ https://ncbi.nlm.nih.gov/pubmed/26774838 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jinorgbio.2015.12.019 |
| Tagit: |
Lisää tagi
Ei tageja, Lisää ensimmäinen tagi!
|