cAMP/CREB-regulated LINC00473 marks LKB1-inactivated lung cancer and mediates tumor growth

The LKB1 tumor suppressor gene is frequently mutated and inactivated in non–small cell lung cancer (NSCLC). Loss of LKB1 promotes cancer progression and influences therapeutic responses in preclinical studies; however, specific targeted therapies for lung cancer with LKB1 inactivation are currently...

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Bibliografiska uppgifter
I publikationen:J Clin Invest
Huvudupphovsmän: Chen, Zirong, Li, Jian-Liang, Lin, Shuibin, Cao, Chunxia, Gimbrone, Nicholas T., Yang, Rongqiang, Fu, Dongtao A., Carper, Miranda B., Haura, Eric B., Schabath, Matthew B., Lu, Jianrong, Amelio, Antonio L., Cress, W. Douglas, Kaye, Frederic J., Wu, Lizi
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Clinical Investigation 2016
Ämnen:
Research Article
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4887185/
https://ncbi.nlm.nih.gov/pubmed/27140397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI85250
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