cAMP/CREB-regulated LINC00473 marks LKB1-inactivated lung cancer and mediates tumor growth

The LKB1 tumor suppressor gene is frequently mutated and inactivated in non–small cell lung cancer (NSCLC). Loss of LKB1 promotes cancer progression and influences therapeutic responses in preclinical studies; however, specific targeted therapies for lung cancer with LKB1 inactivation are currently...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :J Clin Invest
Главные авторы: Chen, Zirong, Li, Jian-Liang, Lin, Shuibin, Cao, Chunxia, Gimbrone, Nicholas T., Yang, Rongqiang, Fu, Dongtao A., Carper, Miranda B., Haura, Eric B., Schabath, Matthew B., Lu, Jianrong, Amelio, Antonio L., Cress, W. Douglas, Kaye, Frederic J., Wu, Lizi
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Clinical Investigation 2016
Предметы:
Research Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4887185/
https://ncbi.nlm.nih.gov/pubmed/27140397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI85250
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы