cAMP/CREB-regulated LINC00473 marks LKB1-inactivated lung cancer and mediates tumor growth

The LKB1 tumor suppressor gene is frequently mutated and inactivated in non–small cell lung cancer (NSCLC). Loss of LKB1 promotes cancer progression and influences therapeutic responses in preclinical studies; however, specific targeted therapies for lung cancer with LKB1 inactivation are currently...

Cijeli opis

Spremljeno u:
Bibliografski detalji
Izdano u:J Clin Invest
Glavni autori: Chen, Zirong, Li, Jian-Liang, Lin, Shuibin, Cao, Chunxia, Gimbrone, Nicholas T., Yang, Rongqiang, Fu, Dongtao A., Carper, Miranda B., Haura, Eric B., Schabath, Matthew B., Lu, Jianrong, Amelio, Antonio L., Cress, W. Douglas, Kaye, Frederic J., Wu, Lizi
Format: Artigo
Jezik:Inglês
Izdano: American Society for Clinical Investigation 2016
Teme:
Research Article
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4887185/
https://ncbi.nlm.nih.gov/pubmed/27140397
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI85250
Oznake: Dodaj oznaku
Bez oznaka, Budi prvi tko označuje ovaj zapis!

Similar Items