CD62L(+) NKT cells have prolonged persistence and antitumor activity in vivo

Vα24-invariant natural killer T cells (NKTs) localize to tumors and have inherent antitumor properties, making them attractive chimeric antigen receptor (CAR) carriers for redirected cancer immunotherapy. However, clinical application of CAR-NKTs has been impeded, as mechanisms responsible for NKT e...

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Bibliographic Details
Published in:J Clin Invest
Main Authors: Tian, Gengwen, Courtney, Amy N., Jena, Bipulendu, Heczey, Andras, Liu, Daofeng, Marinova, Ekaterina, Guo, Linjie, Xu, Xin, Torikai, Hiroki, Mo, Qianxing, Dotti, Gianpietro, Cooper, Laurence J., Metelitsa, Leonid S.
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2016
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4887157/
https://ncbi.nlm.nih.gov/pubmed/27183388
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI83476
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