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IL-21 selectively protects CD62L+ NKT cells and enhances their effector functions for adoptive immunotherapy
T cells expressing CD19-specific chimeric antigen receptors (CARs) produce high remission rates in B-cell lymphoma, but frequent disease recurrence and challenges in generating sufficient numbers of autologous CAR-T cells necessitate the development of alternative therapeutic effectors. Vα24-invaria...
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| Publicado no: | J Immunol |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2018
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6143411/ https://ncbi.nlm.nih.gov/pubmed/30111631 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1800429 |
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