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Invariant NKT cells with chimeric antigen receptor provide a novel platform for safe and effective cancer immunotherapy
Advances in the design of chimeric antigen receptors (CARs) have improved the antitumor efficacy of redirected T cells. However, functional heterogeneity of CAR T cells limits their therapeutic potential and is associated with toxicity. We proposed that CAR expression in Vα24-invariant natural kille...
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| Main Authors: | , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Society of Hematology
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4215313/ https://ncbi.nlm.nih.gov/pubmed/25049283 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2013-11-541235 |
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