IL-15 protects NKT cells from inhibition by tumor-associated macrophages and enhances antimetastatic activity

Vα24-invariant NKT cells inhibit tumor growth by targeting tumor-associated macrophages (TAMs). Tumor progression therefore requires that TAMs evade NKT cell activity through yet-unknown mechanisms. Here we report that a subset of cells in neuroblastoma (NB) cell lines and primary tumors expresses m...

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Detalhes bibliográficos
Main Authors: Liu, Daofeng, Song, Liping, Wei, Jie, Courtney, Amy N., Gao, Xiuhua, Marinova, Ekaterina, Guo, Linjie, Heczey, Andras, Asgharzadeh, Shahab, Kim, Eugene, Dotti, Gianpietro, Metelitsa, Leonid S.
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Clinical Investigation 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3366399/
https://ncbi.nlm.nih.gov/pubmed/22565311
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1172/JCI59535
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