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Palladium-Catalyzed Selective α-Alkenylation of Pyridylmethyl Ethers with Vinyl Bromides

An efficient palladium-catalyzed α-alkenylation of pyridylmethyl ethers with vinyl bromides is presented. A Pd/NIXANTPHOS-based catalyst system enables a mild and chemoselective coupling between a variety of pyridylmethyl ethers and vinyl bromides in good to excellent yields. Under the mild conditio...

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Bibliografiske detaljer
Udgivet i:Org Lett
Main Authors: Yang, Xiaodong, Kim, Byeong-Seon, Li, Minyan, Walsh, Patrick J.
Format: Artigo
Sprog:Inglês
Udgivet: 2016
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4887130/
https://ncbi.nlm.nih.gov/pubmed/27160421
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.orglett.6b00815
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