The TIP60 complex regulates bivalent chromatin recognition by 53BP1 through direct H4K20me binding and H2AK15 acetylation

The NuA4/TIP60 acetyltransferase complex is a key regulator of genome expression and stability. Here, we identified MBTD1 as a new stable subunit of the complex and gleaned intriguing insights into TIP60’s function. Harboring a histone reader domain for H4K20me1/2, MBTD1 allows TIP60 to associate wi...

ver descrição completa

Na minha lista:
Detalhes bibliográficos
Publicado no:Mol Cell
Main Authors: Jacquet, Karine, Fradet-Turcotte, Amélie, Avvakumov, Nikita, Lambert, Jean-Philippe, Roques, Céline, Pandita, Raj K., Paquet, Eric, Herst, Pauline, Gingras, Anne-Claude, Pandita, Tej K., Legube, Gaëlle, Doyon, Yannick, Durocher, Daniel, Côté, Jacques
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4887106/
https://ncbi.nlm.nih.gov/pubmed/27153538
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2016.03.031
Tags: Adicionar Tag
Sem tags, seja o primeiro a adicionar uma tag!

Registos relacionados