53BP1 is a reader of the DNA damage-induced H2A Lys15 ubiquitin mark

53BP1 (TP53BP1) is a chromatin-associated factor that promotes immunoglobulin class switching and DNA double-strand break (DSB) repair by non-homologous end joining. To accomplish its function in DNA repair, 53BP1 accumulates at DSB sites downstream of the RNF168 ubiquitin ligase. How ubiquitin recr...

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Autors principals: Fradet-Turcotte, Amélie, Canny, Marella D., Escribano-Díaz, Cristina, Orthwein, Alexandre, Leung, Charles C.Y., Huang, Hao, Landry, Marie-Claude, Kitevski-LeBlanc, Julianne, Noordermeer, Sylvie M., Sicheri, Frank, Durocher, Daniel
Format: Artigo
Idioma:Inglês
Publicat: 2013
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Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3955401/
https://ncbi.nlm.nih.gov/pubmed/23760478
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12318
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