טוען...
53BP1 is a reader of the DNA damage-induced H2A Lys15 ubiquitin mark
53BP1 (TP53BP1) is a chromatin-associated factor that promotes immunoglobulin class switching and DNA double-strand break (DSB) repair by non-homologous end joining. To accomplish its function in DNA repair, 53BP1 accumulates at DSB sites downstream of the RNF168 ubiquitin ligase. How ubiquitin recr...
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| Main Authors: | , , , , , , , , , , |
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| פורמט: | Artigo |
| שפה: | Inglês |
| יצא לאור: |
2013
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| נושאים: | |
| גישה מקוונת: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3955401/ https://ncbi.nlm.nih.gov/pubmed/23760478 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature12318 |
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