Efficient Ligation of the Schistosoma Hammerhead Ribozyme

par Canny, Marella D., Jucker, Fiona M., Pardi, Arthur
Publié 2007

Metal ion specificities for folding and cleavage activity in the Schistosoma hammerhead ribozyme

par Boots, Jennifer L., Canny, Marella D., Azimi, Ehsan, Pardi, Arthur
Publié 2008

Solution structure of tRNA(Val) from refinement of homology model against residual dipolar coupling and SAXS data

par Grishaev, Alexander, Ying, Jinfa, Canny, Marella D., Pardi, Arthur, Bax, Ad
Publié 2008

A dynamic allosteric pathway underlies Rad50 ABC ATPase function in DNA repair

par Boswell, Zachary K., Rahman, Samiur, Canny, Marella D., Latham, Michael P.
Publié dans Sci Rep (2018)

A Survey of Reported Disease-Related Mutations in the MRE11-RAD50-NBS1 Complex

par Rahman, Samiur, Canny, Marella D., Buschmann, Tanner A., Latham, Michael P.
Publié dans Cells (2020)

Mutation of Conserved Mre11 Residues Alter Protein Dynamics to Separate Nuclease Functions

par Rahman, Samiur, Beikzadeh, Mahtab, Canny, Marella D., Kaur, Navneet, Latham, Michael P.
Publié dans J Mol Biol (2020)

Adjacent mutations in the archaeal Rad50 ABC ATPase D-loop disrupt allosteric regulation of ATP hydrolysis through different mechanisms

par Boswell, Zachary K, Canny, Marella D, Buschmann, Tanner A, Sang, Julie, Latham, Michael P
Publié dans Nucleic Acids Res (2020)

A therapeutic aptamer inhibits angiogenesis by specifically targeting the heparin binding domain of VEGF(165)

par Lee, Joon-Hwa, Canny, Marella D., De Erkenez, Andrea, Krilleke, Dominik, Ng, Yin-Shan, Shima, David T., Pardi, Arthur, Jucker, Fiona
Publié 2005

Nucleosome Acidic Patch Promotes RNF168- and RING1B/BMI1-Dependent H2AX and H2A Ubiquitination and DNA Damage Signaling

par Leung, Justin W., Agarwal, Poonam, Canny, Marella D., Gong, Fade, Robison, Aaron D., Finkelstein, Ilya J., Durocher, Daniel, Miller, Kyle M.
Publié 2014

53BP1 is a reader of the DNA damage-induced H2A Lys15 ubiquitin mark

par Fradet-Turcotte, Amélie, Canny, Marella D., Escribano-Díaz, Cristina, Orthwein, Alexandre, Leung, Charles C.Y., Huang, Hao, Landry, Marie-Claude, Kitevski-LeBlanc, Julianne, Noordermeer, Sylvie M., Sicheri, Frank, Durocher, Daniel
Publié 2013

The RNF168 paralog RNF169 defines a new class of ubiquitylated histone reader involved in the response to DNA damage

par Kitevski-LeBlanc, Julianne, Fradet-Turcotte, Amélie, Kukic, Predrag, Wilson, Marcus D, Portella, Guillem, Yuwen, Tairan, Panier, Stephanie, Duan, Shili, Canny, Marella D, van Ingen, Hugo, Arrowsmith, Cheryl H, Rubinstein, John L, Vendruscolo, Michele, Durocher, Daniel, Kay, Lewis E
Publié dans eLife (2017)

Structure and mechanism of action of the hydroxy aryl aldehyde class of IRE1 endoribonuclease inhibitors

par Sanches, Mario, Duffy, Nicole M., Talukdar, Manisha, Thevakumaran, Nero, Chiovitti, David, Canny, Marella D., Lee, Kenneth, Kurinov, Igor, Uehling, David, Al-awar, Rima, Poda, Gennadiy, Prakesch, Michael, Wilson, Brian, Tam, Victor, Schweitzer, Colleen, Toro, Andras, Lucas, Julie L., Vuga, Danka, Lehmann, Lynn, Durocher, Daniel, Zeng, Qingping, Patterson, John B., Sicheri, Frank
Publié dans Nat Commun (2014)

Inhibition of 53BP1 favors homology-dependent DNA repair and increases CRISPR-Cas9 genome-editing efficiency

par Canny, Marella D., Moatti, Nathalie, Wan, Leo C.K., Fradet-Turcotte, Amélie, Krasner, Danielle, Mateos-Gomez, Pedro A., Zimmermann, Michal, Orthwein, Alexandre, Juang, Yu-Chi, Zhang, Wei, Noordermeer, Sylvie M., Seclen, Eduardo, Wilson, Marcus D., Vorobyov, Andrew, Munro, Meagan, Ernst, Andreas, Ng, Timothy F., Cho, Tiffany, Cannon, Paula M., Sidhu, Sachdev S., Sicheri, Frank, Durocher, Daniel
Publié dans Nat Biotechnol (2017)

The MMS22L-TONSL complex mediates recovery from replication stress and homologous recombination

par O’Donnell, Lara, Panier, Stephanie, Wildenhain, Jan, Tkach, Johnny M., Al-Hakim, Abdallah, Landry, Marie-Claude, Escribano-Diaz, Cristina, Szilard, Rachel K., Young, Jordan T. F., Munro, Meagan, Canny, Marella D., Kolas, Nadine K., Zhang, Wei, Harding, Shane M., Ylanko, Jarkko, Mendez, Megan, Mullin, Michael, Sun, Thomas, Habermann, Bianca, Datti, Alessandro, Bristow, Robert G., Gingras, Anne-Claude, Tyers, Michael D., Brown, Grant W., Durocher, Daniel
Publié 2010