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HBO1 HAT COMPLEXES TARGET CHROMATIN THROUGHOUT GENE CODING REGIONS VIA MULTIPLE PHD FINGER INTERACTIONS WITH HISTONE H3 TAIL
The HBO1 HAT protein is the major source of histone H4 acetylation in vivo and has been shown to play critical roles in gene regulation and DNA replication. A distinctive characteristic of HBO1 HAT complexes is the presence of three PHD finger domains in two different subunits: tumor suppressor prot...
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| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
2009
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| Teme: | |
| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2677731/ https://ncbi.nlm.nih.gov/pubmed/19187766 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2009.01.007 |
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