Interleukin-2 Therapy Induces CD4 Downregulation, Which Decreases Circulating CD4 T Cell Counts, in African Green Monkeys

African green monkeys (AGMs) are natural hosts of simian immunodeficiency virus (SIV(AGM)). Because these animals do not develop simian AIDS despite maintaining high viral loads, there is considerable interest in determining how these animals have evolved to avoid SIV disease progression. Unlike non...

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Vydáno v:J Virol
Hlavní autoři: Mudd, Joseph C., Perkins, Molly R., DiNapoli, Sarah R., Hirsch, Vanessa M., Brenchley, Jason M.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2016
Témata:
Pathogenesis and Immunity
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4886792/
https://ncbi.nlm.nih.gov/pubmed/27053558
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00057-16
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